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Bone Marrow CD11c(+) Cell-Derived Amphiregulin Promotes Pulmonary Fibrosis

Amphiregulin (AREG), an epidermal growth factor receptor ligand, is implicated in tissue repair and fibrosis but its cellular source and role in regeneration vs. fibrosis remain unclear. In this study we hypothesize that AREG induced in bone marrow derived CD11c+ cells is essential for pulmonary fib...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Ding, Lin, Liu, Tianju, Wu, Zhe, Hu, Biao, Nakashima, Taku, Ullenbruch, Matthew, De Los Santos, Francina Gonzalez, Phan, Sem H.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912903/
https://ncbi.nlm.nih.gov/pubmed/27206766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502479
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