A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibition

Anesthetic, GABA-active neurosteroids potently augment GABA(A) receptor function, leading to important behavioral consequences. Neurosteroids and their synthetic analogues are also models for a wide variety of cell-permeant neuroactive compounds. Cell permeation and compartmentalization raise the po...

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Pubblicato in:Neuropharmacology
Autori principali: Jiang, Xiaoping, Shu, Hong-Jin, Krishnan, Kathiresan, Qian, Mingxing, Taylor, Amanda A., Covey, Douglas F., Zorumski, Charles F., Mennerick, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912882/
https://ncbi.nlm.nih.gov/pubmed/27114255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.04.031
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