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Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABA(A) receptor function

RATIONALE: Neurosteroids and likely other lipid modulators access transmembrane sites on the GABA(A) receptor (GABA(A)R) by partitioning into and diffusing through the plasma membrane. Therefore, specific components of the plasma membrane may affect the potency or efficacy of neurosteroid-like modul...

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Bibliografiska uppgifter
I publikationen:Psychopharmacology (Berl)
Huvudupphovsmän: Mennerick, Steven, Taylor, Amanda A., Zorumski, Charles F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439103/
https://ncbi.nlm.nih.gov/pubmed/24553581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3486-5
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