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Robust estimates of overall immune-repertoire diversity from high-throughput measurements on samples

The diversity of an organism's B- and T-cell repertoires is both clinically important and a key measure of immunological complexity. However, diversity is hard to estimate by current methods, because of inherent uncertainty in the number of B- and T-cell clones that will be missing from a blood...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kaplinsky, Joseph, Arnaout, Ramy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912625/
https://ncbi.nlm.nih.gov/pubmed/27302887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11881
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