α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy

Multiple system atrophy (MSA) is a rare atypical parkinsonian disorder characterized by a rapidly progressing clinical course and at present without any efficient therapy. Neuropathologically, myelin loss and neurodegeneration are associated with α-synuclein accumulation in oligodendrocytes, but und...

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Udgivet i:Acta Neuropathol
Main Authors: Ettle, Benjamin, Kerman, Bilal E., Valera, Elvira, Gillmann, Clarissa, Schlachetzki, Johannes C.M., Reiprich, Simone, Büttner, Christian, Ekici, Arif B., Reis, André, Wegner, Michael, Bäuerle, Tobias, Riemenschneider, Markus J., Masliah, Eliezer, Gage, Fred H., Winkler, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912450/
https://ncbi.nlm.nih.gov/pubmed/27059609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1572-y
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