Prdm4 induction by the small molecule butein promotes white adipose tissue browning

Increasing the thermogenic activity of adipocytes holds promise as an approach to combating human obesity and its related metabolic diseases. We identified PR domain containing 4 (Prdm4) induction by the small molecule butein as a means to induce uncoupling protein 1 expression, increase energy expe...

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Bibliografiske detaljer
Udgivet i:Nat Chem Biol
Main Authors: Song, No-Joon, Choi, Seri, Rajbhandari, Prashant, Chang, Seo-Hyuk, Kim, Suji, Vergnes, Laurent, Kwon, So-Mi, Yoon, Jung-Hoon, Lee, Suk-Chan, Ku, Jin-Mo, Lee, Jeong-Soo, Reue, Karen, Koo, Seung-Hoi, Tontonoz, Peter, Park, Kye Won
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912433/
https://ncbi.nlm.nih.gov/pubmed/27159578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2081
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