Prdm4 induction by the small molecule butein promotes white adipose tissue browning

Increasing the thermogenic activity of adipocytes holds promise as an approach to combating human obesity and its related metabolic diseases. We identified PR domain containing 4 (Prdm4) induction by the small molecule butein as a means to induce uncoupling protein 1 expression, increase energy expe...

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I publikationen:Nat Chem Biol
Huvudupphovsmän: Song, No-Joon, Choi, Seri, Rajbhandari, Prashant, Chang, Seo-Hyuk, Kim, Suji, Vergnes, Laurent, Kwon, So-Mi, Yoon, Jung-Hoon, Lee, Suk-Chan, Ku, Jin-Mo, Lee, Jeong-Soo, Reue, Karen, Koo, Seung-Hoi, Tontonoz, Peter, Park, Kye Won
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912433/
https://ncbi.nlm.nih.gov/pubmed/27159578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2081
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