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Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate

Nonsense-mediated RNA decay (NMD) is a highly conserved pathway that selectively degrades specific subsets of RNA transcripts. Here, we provide evidence that NMD regulates early human developmental cell fate. We found that NMD factors tend to be expressed at higher levels in human pluripotent cells...

詳細記述

保存先:
書誌詳細
出版年:Stem Cell Reports
主要な著者: Lou, Chih-Hong, Dumdie, Jennifer, Goetz, Alexandra, Shum, Eleen Y., Brafman, David, Liao, Xiaoyan, Mora-Castilla, Sergio, Ramaiah, Madhuvanthi, Cook-Andersen, Heidi, Laurent, Louise, Wilkinson, Miles F.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912386/
https://ncbi.nlm.nih.gov/pubmed/27304915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.05.008
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