Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4(+) T-Cell Activation

The transcription factor BCL11B/CTIP2 is a major regulatory protein implicated in various aspects of development, function and survival of T cells. Mitogen-activated protein kinase (MAPK)-mediated phosphorylation and SUMOylation modulate BCL11B transcriptional activity, switching it from a repressor...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Dubuissez, Marion, Loison, Ingrid, Paget, Sonia, Vorng, Han, Ait-Yahia, Saliha, Rohr, Olivier, Tsicopoulos, Anne, Leprince, Dominique
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911745/
https://ncbi.nlm.nih.gov/pubmed/27161321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00062-16
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