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Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1(STEM) Mouse

Defining the molecular regulators of hematopoietic stem and progenitor cells (HSPCs) requires in vivo functional analyses. Competitive bone marrow transplants (BMTs) compare control and test HSPCs to demonstrate the functional role of a genetic change or chemical perturbation. Competitive BMT is ena...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Mercier, Francois E., Sykes, David B., Scadden, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911492/
https://ncbi.nlm.nih.gov/pubmed/27185283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.04.010
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