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Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1STEM Mouse

Summary: Defining the molecular regulators of hematopoietic stem and progenitor cells (HSPCs) requires in vivo functional analyses. Competitive bone marrow transplants (BMTs) compare control and test HSPCs to demonstrate the functional role of a genetic change or chemical perturbation. Competitive B...

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Bibliographische Detailangaben
Hauptverfasser: Francois E. Mercier, David B. Sykes, David T. Scadden
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016-06-01
Schriftenreihe:Stem Cell Reports
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2213671116300352
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