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How to Build a Complex, Functional Propeller Protein From Parts
By combining ancestral sequence reconstruction and in vitro evolution, Smock et al. identified single motifs that assemble into a functional five-bladed β-propeller, and a likely route for conversion into the more complex, extant single chain fusion. Interestingly, although sequence diversification...
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| Pubblicato in: | Trends Biochem Sci |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4911255/ https://ncbi.nlm.nih.gov/pubmed/26971075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.02.010 |
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