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How to Build a Complex, Functional Propeller Protein From Parts

By combining ancestral sequence reconstruction and in vitro evolution, Smock et al. identified single motifs that assemble into a functional five-bladed β-propeller, and a likely route for conversion into the more complex, extant single chain fusion. Interestingly, although sequence diversification...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Biochem Sci
Prif Awdur: Clark, Patricia L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911255/
https://ncbi.nlm.nih.gov/pubmed/26971075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.02.010
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