Src Is a Potential Therapeutic Target in Endocrine-Resistant Breast Cancer Exhibiting Low Estrogen Receptor-Mediated Transactivation

Despite the effectiveness of endocrine therapies in estrogen receptor positive (ER+) breast cancer, approximately 40% of patients relapse. Previously, we identified the Focal-adhesion kinase canonical pathway as a major contributor of resistance to estrogen deprivation and cellular-sarcoma kinase (c...

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Vydáno v:PLoS One
Hlavní autoři: Guest, Stephanie K., Ribas, Ricardo, Pancholi, Sunil, Nikitorowicz-Buniak, Joanna, Simigdala, Nikiana, Dowsett, Mitch, Johnston, Stephen R., Martin, Lesley-Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911087/
https://ncbi.nlm.nih.gov/pubmed/27308830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157397
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