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Enhanced Th1/Th17 Functions of CD161(+) CD8(+) T Cells in Mucosal Tissues of Rhesus Macaques

Expression of the C-type lectin-like receptor CD161 by human T cells is associated with type-17 responses, which play critical regulatory roles in immunity and inflammation at mucosal sites. However, the functions of CD161-expressing T cells in macaques, the pre-clinical model of several human disea...

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Bibliographic Details
Published in:PLoS One
Main Author: Rout, Namita
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911052/
https://ncbi.nlm.nih.gov/pubmed/27309719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157407
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