HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition

In the RV144 vaccine trial, two antibody responses were found to correlate with HIV-1 acquisition. Because human leukocyte antigen (HLA) class II–restricted CD4(+) T cells are involved in antibody production, we tested whether HLA class II genotypes affected HIV-1–specific antibody levels and HIV-1...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Transl Med
Egile Nagusiak: Prentice, Heather A., Tomaras, Georgia D., Geraghty, Daniel E., Apps, Richard, Fong, Youyi, Ehrenberg, Philip K., Rolland, Morgane, Kijak, Gustavo H., Krebs, Shelly J., Nelson, Wyatt, DeCamp, Allan, Shen, Xiaoying, Yates, Nicole L., Zolla-Pazner, Susan, Nitayaphan, Sorachai, Rerks-Ngarm, Supachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Ferrari, Guido, Juliana McElrath, M., Montefiori, David C., Bailer, Robert T., Koup, Richard A., O’Connell, Robert J., Robb, Merlin L., Michael, Nelson L., Gilbert, Peter B., Kim, Jerome H., Thomas, Rasmi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911012/
https://ncbi.nlm.nih.gov/pubmed/26180102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aab4005
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