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Bias Characterization in Probabilistic Genotype Data and Improved Signal Detection with Multiple Imputation

Missing data are an unavoidable component of modern statistical genetics. Different array or sequencing technologies cover different single nucleotide polymorphisms (SNPs), leading to a complicated mosaic pattern of missingness where both individual genotypes and entire SNPs are sporadically absent....

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Palmer, Cameron, Pe’er, Itsik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910998/
https://ncbi.nlm.nih.gov/pubmed/27310603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006091
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