IFN-γ–Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells

Rationale: Pulmonary sarcoidosis is classically defined by T-helper (Th) cell type 1 inflammation (e.g., IFN-γ production by CD4(+) effector T cells). Recently, IL-17A–secreting cells have been found in lung lavage, invoking Th17 immunity in sarcoidosis. Studies also identified IL-17A–secreting cell...

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Dades bibliogràfiques
Publicat a:Am J Respir Crit Care Med
Autors principals: Ramstein, Joris, Broos, Caroline E., Simpson, Laura J., Ansel, K. Mark, Sun, Sara A., Ho, Melissa E., Woodruff, Prescott G., Bhakta, Nirav R., Christian, Laura, Nguyen, Christine P., Antalek, Bobby J., Benn, Bryan S., Hendriks, Rudi W., van den Blink, Bernt, Kool, Mirjam, Koth, Laura L.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910899/
https://ncbi.nlm.nih.gov/pubmed/26649486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201507-1499OC
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