IFN-γ–Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells

Rationale: Pulmonary sarcoidosis is classically defined by T-helper (Th) cell type 1 inflammation (e.g., IFN-γ production by CD4(+) effector T cells). Recently, IL-17A–secreting cells have been found in lung lavage, invoking Th17 immunity in sarcoidosis. Studies also identified IL-17A–secreting cell...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Respir Crit Care Med
Päätekijät: Ramstein, Joris, Broos, Caroline E., Simpson, Laura J., Ansel, K. Mark, Sun, Sara A., Ho, Melissa E., Woodruff, Prescott G., Bhakta, Nirav R., Christian, Laura, Nguyen, Christine P., Antalek, Bobby J., Benn, Bryan S., Hendriks, Rudi W., van den Blink, Bernt, Kool, Mirjam, Koth, Laura L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Thoracic Society 2016
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910899/
https://ncbi.nlm.nih.gov/pubmed/26649486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201507-1499OC
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