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Two-Pore Channels: Lessons from Mutant Mouse Models

Recent interest in two-pore channels (TPCs) has resulted in a variety of studies dealing with the functional role and mechanism of action of these endo-lysosomal proteins in diverse physiological processes. With the availability of mouse lines harbouring mutant alleles for Tpcnl and/or Tpcn2 genes,...

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Bibliographic Details
Published in:Messenger (Los Angel)
Main Authors: Ruas, Margarida, Galione, Antony, Parrington, John
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910865/
https://ncbi.nlm.nih.gov/pubmed/27330869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/msr.2015.1041
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