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Calcium signaling via two-pore channels: local or global, that is the question

Recently, we identified, for the first time, two-pore channels (TPCs, TPCN for gene name) as a novel family of nicotinic acid adenine dinucleotide phosphate (NAADP)-gated, endolysosome-targeted calcium release channels. Significantly, three subtypes of TPCs have been characterized, TPC1-3, with each...

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Autors principals: Zhu, Michael X., Ma, Jianjie, Parrington, John, Calcraft, Peter J., Galione, Antony, Evans, A. Mark
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838574/
https://ncbi.nlm.nih.gov/pubmed/20018950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00475.2009
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