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Tissue barriers and novel approaches to achieve hepatoselectivity of subcutaneously-injected insulin therapeutics
Current subcutaneously (s.c.)-injected insulin (INS) products result in a hyperinsulin exposure to peripheral tissues (skeletal muscle and adipose) while INS hardly accesses to liver after injection. This unphysiological distribution raises risks of hypoglycemia episode and causes weight gain after...
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| Publicado no: | Tissue Barriers |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910833/ https://ncbi.nlm.nih.gov/pubmed/27358753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21688370.2016.1156804 |
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