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Toll-like receptor (TLR4) Asp299Gly and Thr399Ile polymorphisms in relation to clinical falciparum malaria among Nigerian children: a multisite cross-sectional immunogenetic study in Lagos

INTRODUCTION: This study determined the association of TLR4 Asp299Gly and Thr399Ile with uncomplicated and severe malaria among Nigerian children of similar ethnic background in Lagos. The association of these SNPs with high parasite density, malnutrition, hyperpyrexia and anaemia was also investiga...

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Detalhes bibliográficos
Publicado no:Genes Environ
Main Authors: Iwalokun, Bamidele Abiodun, Oluwadun, Afolabi, Iwalokun, Senapon Olusola, Agomo, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910769/
https://ncbi.nlm.nih.gov/pubmed/27350800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-015-0002-z
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