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TLR4 mutations (Asp299Gly and Thr399Ile) are not associated with ankylosing spondylitis

BACKGROUND: Immunoregulatory genes and Gram negative gut bacteria are thought to be important in disease expression in ankylosing spondylitis (AS). OBJECTIVE: To compare the frequency of two common and functional TLR4 mutations (Asp299Gly, and Thr399Ile) between patients with AS and HLA‐B27 healthy...

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Библиографические подробности
Главные авторы: Adam, R, Sturrock, R D, Gracie, J A
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Group 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798236/
https://ncbi.nlm.nih.gov/pubmed/16837493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.045476
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