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A novel approach of longitudinal adverse event evaluation in oncology clinical trials: the Toxicity over Time (ToxT) analysis of clinical trials N9741 and 979254 (Alliance)

BACKGROUND: Traditional methods of reporting adverse events (AEs) in clinical trials are inadequate for modern oncology therapies with chronic administration. Conventional analysis and display of maximum grade AEs do not capture toxicity profiles that evolve over time or longer lasting, lower grade...

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Bibliografiset tiedot
Julkaisussa:Lancet Oncol
Päätekijät: Thanarajasingam, Gita, Atherton, Pamela J., Novotny, Paul J., Loprinzi, Charles L., Sloan, Jeff A., Grothey, Axel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910515/
https://ncbi.nlm.nih.gov/pubmed/27083333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(16)00038-3
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