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A fully human IgG1 anti-PD-L1 MAb in an in vitro assay enhances antigen-specific T-cell responses

Monoclonal antibodies (MAbs) that interfere with checkpoint molecules are being investigated for the treatment of infectious diseases and cancer, with the aim of enhancing the function of an impaired immune system. Avelumab (MSB0010718C) is a fully human IgG1 MAb targeting programmed death-ligand 1...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Clin Transl Immunology
मुख्य लेखकों: Grenga, Italia, Donahue, Renee N, Lepone, Lauren M, Richards, Jacob, Schlom, Jeffrey
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910121/
https://ncbi.nlm.nih.gov/pubmed/27350882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.27
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