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58-F, a flavanone from Ophiopogon japonicus, prevents hepatocyte death by decreasing lysosomal membrane permeability
Lysosome membrane permeabilization (LMP) has been implicated in cell death. In the present study, we investigated the relationship between cell death and H(2)O(2)-/CCl(4)-induced LMP in hepatocytes in vitro and following acute liver injury in vivo. The key finding was that H(2)O(2) triggered LMP by...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910050/ https://ncbi.nlm.nih.gov/pubmed/27306715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27875 |
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