The long non-coding RNA – HIF1A-AS2 facilitates the maintenance of mesenchymal glioblastoma stem-like cells in hypoxic niches

Long-non-coding RNAs (lncRNAs) have an undefined role in the pathobiology of glioblastoma multiforme (GBM). These tumors are genetically and phenotypically heterogeneous with transcriptome subtype-specific GBM stem-like cells (GSCs) that adapt to the brain tumor microenvironment, including hypoxic n...

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Foilsithe in:Cell Rep
Main Authors: Mineo, Marco, Ricklefs, Franz, Rooj, Arun K., Lyons, Shawn M., Ivanov, Pavel, Ansari, Khairul I., Nakano, Ichiro, Chiocca, E. Antonio, Godlewski, Jakub, Bronisz, Agnieszka
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909547/
https://ncbi.nlm.nih.gov/pubmed/27264189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.018
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