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Extracellular vesicles from high grade glioma exchange diverse pro-oncogenic signals that maintain intratumoral heterogeneity

A lack of experimental models of tumor heterogeneity limits our knowledge of the complex subpopulation dynamics within the tumor ecosystem. In high grade gliomas (HGG), distinct hierarchical cell populations arise from different glioma stem-like cell (GSC) subpopulations. Extracellular vesicles (EV)...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Ricklefs, Franz, Mineo, Marco, Rooj, Arun K., Nakano, Ichiro, Charest, Al, Weissleder, Ralph, Breakefield, Xandra O., Chiocca, E. Antonio, Godlewski, Jakub, Bronisz, Agnieszka
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873326/
https://ncbi.nlm.nih.gov/pubmed/27013191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3432
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