FOXC1-induced Gli2 activation: A non-canonical pathway contributing to stemness and anti-Hedgehog resistance in basal-like breast cancer

The Forkhead box C1 (FOXC1) transcriptional factor is a critical biomarker for basal-like breast cancer (BLBC). We recently reported that FOXC1 promotes cancer stem cell properties in BLBC by activating Smoothened (SMO)-independent Hedgehog (Hh) signaling, suggesting a FOXC1-mediated mechanism for B...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Oncol
Egile Nagusiak: Han, Bingchen, Qu, Ying, Yu-Rice, Yi, Johnson, Jeffrey, Cui, Xiaojiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2016
Gaiak:
Author's View
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909418/
https://ncbi.nlm.nih.gov/pubmed/27314088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1131668
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