FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer

The mesoderm- and epithelial-mesenchymal transition-associated transcription factor FOXC1 is specifically overexpressed in basal-like breast cancer (BLBC), but its biochemical function is not understood. Here we demonstrate that FOXC1 controls cancer stem cell (CSC) properties enriched in BLBC cells...

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Publicado no:Cell Rep
Main Authors: Han, Bingchen, Qu, Ying, Jin, Yanli, Yu, Yi, Deng, Nan, Wawrowsky, Kolja, Zhang, Xiao, Li, Na, Bose, Shikha, Wang, Qiang, Sakkiah, Sugunadevi, Abrol, Ravinder, Jensen, Tor W., Berman, Benjamin, Tanaka, Hisashi, Johnson, Jeffrey, Gao, Bowen, Hao, Jijun, Liu, Zhenqiu, Buttyan, Ralph, Ray, Partha S., Hung, Mien-Chie, Giuliano, Armando E., Cui, Xiaojiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806384/
https://ncbi.nlm.nih.gov/pubmed/26565916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.063
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