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Heparanase tailors syndecan for exosome production

Exosomes are secreted vesicles involved in signaling processes. The biogenesis of a class of these vesicles depends on syntenin and syndecans. Heparanase acts as a regulator of the syndecan-syntenin-exosome biogenesis pathway. The upregulation of syntenin and heparanase in cancers may support the su...

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Publicado en:Mol Cell Oncol
Autores principales: David, Guido, Zimmermann, Pascale
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909406/
https://ncbi.nlm.nih.gov/pubmed/27314072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1047556
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