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Heparanase activates the syndecan-syntenin-ALIX exosome pathway

Exosomes are secreted vesicles of endosomal origin involved in signaling processes. We recently showed that the syndecan heparan sulfate proteoglycans control the biogenesis of exosomes through their interaction with syntenin-1 and the endosomal-sorting complex required for transport accessory compo...

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Dettagli Bibliografici
Pubblicato in:Cell Res
Autori principali: Roucourt, Bart, Meeussen, Sofie, Bao, Jie, Zimmermann, Pascale, David, Guido
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387558/
https://ncbi.nlm.nih.gov/pubmed/25732677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.29
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