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Keeping autophagy in cheCK1

Mutant RAS-driven cancer cells cope with proliferative stress by increasing basal autophagy to maintain protein/organelle and energy homeostasis. We recently demonstrated that casein kinase 1 alpha (CK1α), a therapeutically tractable enzyme, is critical for fine-tuning the transcriptional regulation...

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Detalles Bibliográficos
Publicado en:Mol Cell Oncol
Main Authors: Cheong, Jit Kong, Virshup, David M.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909404/
https://ncbi.nlm.nih.gov/pubmed/27314070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1045117
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