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Inhibition of HIV Entry by Targeting the Envelope Transmembrane Subunit gp41

BACKGROUND: The transmembrane subunit of the HIV envelope protein, gp41 is a vulnerable target to inhibit HIV entry. There is one fusion inhibitor T20 (brand name: Fuzeon, generic name: enfuvirtide) available by prescription. However, it has several drawbacks such as a high level of development of d...

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Publicat a:Curr HIV Res
Autors principals: Yi, Hyun Ah, Fochtman, Brian C., Rizzo, Robert C., Jacobs, Amy
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909398/
https://ncbi.nlm.nih.gov/pubmed/26957202
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