Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases

Segmented negative strand RNA viruses of the arena-, bunya- and orthomyxovirus families uniquely carry out viral mRNA transcription by the cap-snatching mechanism. This involves cleavage of host mRNAs close to their capped 5′ end by an endonuclease (EN) domain located in the N-terminal region of the...

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Publicat a:PLoS Pathog
Autors principals: Reguera, Juan, Gerlach, Piotr, Rosenthal, Maria, Gaudon, Stephanie, Coscia, Francesca, Günther, Stephan, Cusack, Stephen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909276/
https://ncbi.nlm.nih.gov/pubmed/27304209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005636
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