Reduced transcription of the ferredoxin gene in metronidazole-resistant Trichomonas vaginalis.
Metronidazole [1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole] is used to treat infections caused by Trichomonas vaginalis, a sexually transmitted human parasite. This drug is administered in an inactive form and is reduced to its cytotoxic form within the hydrogenosome, an unusual organelle found in...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1374901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4402 |
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