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Reduced transcription of the ferredoxin gene in metronidazole-resistant Trichomonas vaginalis.

Metronidazole [1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole] is used to treat infections caused by Trichomonas vaginalis, a sexually transmitted human parasite. This drug is administered in an inactive form and is reduced to its cytotoxic form within the hydrogenosome, an unusual organelle found in...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Quon, D V, d'Oliveira, C E, Johnson, P J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1374901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4402
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