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Meta-analytic framework for sparse K-means to identify disease subtypes in multiple transcriptomic studies

Disease phenotyping by omics data has become a popular approach that potentially can lead to better personalized treatment. Identifying disease subtypes via unsupervised machine learning is the first step towards this goal. In this paper, we extend a sparse K-means method towards a meta-analytic fra...

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Библиографические подробности
Опубликовано в: :J Am Stat Assoc
Главные авторы: Huo, Zhiguang, Ding, Ying, Liu, Silvia, Oesterreich, Steffi, Tseng, George
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908837/
https://ncbi.nlm.nih.gov/pubmed/27330233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01621459.2015.1086354
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