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Methotrexate efficacy, but not its intolerance, is associated with the dose and route of administration

BACKGROUND: There is a lack of published evidence on the importance of methotrexate (MTX) dose and route of administration on both its efficacy and adverse events in children with Juvenile Idiopathic Arthritis (JIA). We aimed to document our clinical practice based on the treat-to-target approach in...

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Detalhes bibliográficos
Publicado no:Pediatr Rheumatol Online J
Main Authors: Fráňová, J., Fingerhutová, Š., Kobrová, K., Srp, R., Němcová, D., Hoza, J., Uher, M., Saifridová, M., Linková, L., Doležalová, P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908704/
https://ncbi.nlm.nih.gov/pubmed/27301536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-016-0099-z
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