Methotrexate efficacy, but not its intolerance, is associated with the dose and route of administration

BACKGROUND: There is a lack of published evidence on the importance of methotrexate (MTX) dose and route of administration on both its efficacy and adverse events in children with Juvenile Idiopathic Arthritis (JIA). We aimed to document our clinical practice based on the treat-to-target approach in...

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Pubblicato in:Pediatr Rheumatol Online J
Autori principali: Fráňová, J., Fingerhutová, Š., Kobrová, K., Srp, R., Němcová, D., Hoza, J., Uher, M., Saifridová, M., Linková, L., Doležalová, P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908704/
https://ncbi.nlm.nih.gov/pubmed/27301536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-016-0099-z
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