Crystal structure of a nucleoside model for the inter­strand cross-link formed by the reaction of 2′-de­oxy­guanosine and an abasic site in duplex DNA

The title compound, 9-[(2R,4S,5R)-4-hy­droxy-5-(hy­droxy­meth­yl)tetra­hydro­furan-2-yl]-2-{[(2R,4S,5R)-4-meth­oxy-5-(meth­oxy­meth­yl)tetra­hydro­furan-2-yl]amino}-1H-purin-6(9H)-one, C(17)H(25)N(5)O(7), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. In the crystal,...

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Bibliographic Details
Published in:Acta Crystallogr E Crystallogr Commun
Main Authors: Catalano, Michael J., Ruddraraju, Kasi Viswanatharaju, Barnes, Charles L., Gates, Kent S.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2016
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908545/
https://ncbi.nlm.nih.gov/pubmed/27308004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S205698901600517X
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