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Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine

Intestinal resident macrophages (Mϕs) regulate gastrointestinal homeostasis via production of an anti-inflammatory cytokine interleukin (IL)-10. Although a constant replenishment by circulating monocytes is required to maintain the pool of resident Mϕs in the colonic mucosa, the homeostatic regulati...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ochi, Takanori, Feng, Yongjia, Kitamoto, Sho, Nagao-Kitamoto, Hiroko, Kuffa, Peter, Atarashi, Koji, Honda, Kenya, Teitelbaum, Daniel H., Kamada, Nobuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908404/
https://ncbi.nlm.nih.gov/pubmed/27302484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27634
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