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Influence maximization in time bounded network identifies transcription factors regulating perturbed pathways

Motivation: To understand the dynamic nature of the biological process, it is crucial to identify perturbed pathways in an altered environment and also to infer regulators that trigger the response. Current time-series analysis methods, however, are not powerful enough to identify perturbed pathways...

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Publié dans:Bioinformatics
Auteurs principaux: Jo, Kyuri, Jung, Inuk, Moon, Ji Hwan, Kim, Sun
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908359/
https://ncbi.nlm.nih.gov/pubmed/27307609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw275
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