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An integer programming framework for inferring disease complexes from network data

Motivation: Unraveling the molecular mechanisms that underlie disease calls for methods that go beyond the identification of single causal genes to inferring larger protein assemblies that take part in the disease process. Results: Here, we develop an exact, integer-programming-based method for asso...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Mazza, Arnon, Klockmeier, Konrad, Wanker, Erich, Sharan, Roded
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908347/
https://ncbi.nlm.nih.gov/pubmed/27307626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw263
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