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A novel method for discovering local spatial clusters of genomic regions with functional relationships from DNA contact maps

Motivation: The three-dimensional structure of genomes makes it possible for genomic regions not adjacent in the primary sequence to be spatially proximal. These DNA contacts have been found to be related to various molecular activities. Previous methods for analyzing DNA contact maps obtained from...

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Pubblicato in:Bioinformatics
Autori principali: Hu, Xihao, Shi, Christina Huan, Yip, Kevin Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908340/
https://ncbi.nlm.nih.gov/pubmed/27307607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw256
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