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Predicting physiologically relevant SH3 domain mediated protein–protein interactions in yeast

Motivation: Many intracellular signaling processes are mediated by interactions involving peptide recognition modules such as SH3 domains. These domains bind to small, linear protein sequence motifs which can be identified using high-throughput experimental screens such as phage display. Binding mot...

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Foilsithe in:Bioinformatics
Main Authors: Jain, Shobhit, Bader, Gary D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908317/
https://ncbi.nlm.nih.gov/pubmed/26861823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw045
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