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The acute and long‐term L‐DOPA effects are independent from changes in the activity of dorsal raphe serotonergic neurons in 6‐OHDA lesioned rats
BACKGROUND AND PURPOSE: L‐DOPA is still the most efficacious pharmacological treatment for Parkinson's disease. However, in the majority of patients receiving long‐term therapy with L‐DOPA, its efficacy is compromised by motor complications, notably L‐DOPA‐induced dyskinesia. Evidence suggests...
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| Publicado en: | Br J Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4908202/ https://ncbi.nlm.nih.gov/pubmed/26805402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13447 |
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