Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance

Osteosarcoma (OS) responds poorly to radiotherapy, but the mechanism is unclear. We found OS tumor tissues expressed high level of protein HIF-1α, a common biological marker indicative of hypoxia. It is known that hypoxic cells are generally radioresistant because of reduced production of irradiatio...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Bone Oncol
Autori principali: Feng, Helin, Wang, Jin, Chen, Wei, Shan, Baoen, Guo, Yin, Xu, Jianfa, Wang, Ling, Guo, Peng, Zhang, Yingze
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908188/
https://ncbi.nlm.nih.gov/pubmed/27335774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2016.03.001
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi