RNA Interference Prevents Autosomal-Dominant Hearing Loss

Hearing impairment is the most common sensory deficit. It is frequently caused by the expression of an allele carrying a single dominant missense mutation. Herein, we show that a single intracochlear injection of an artificial microRNA carried in a viral vector can slow progression of hearing loss f...

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Bibliografiska uppgifter
I publikationen:Am J Hum Genet
Huvudupphovsmän: Shibata, Seiji B., Ranum, Paul T., Moteki, Hideaki, Pan, Bifeng, Goodwin, Alexander T., Goodman, Shawn S., Abbas, Paul J., Holt, Jeffrey R., Smith, Richard J.H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908151/
https://ncbi.nlm.nih.gov/pubmed/27236922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.03.028
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