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The levels of urinary glycosaminoglycans of patients with attenuated and severe type of mucopolysaccharidosis II determined by liquid chromatography-tandem mass spectrometry

Glycosaminoglycans (GAGs) play important roles on the regulation of extracellular signaling, neuronal development, and cartilage maintenance. The extracellular concentration of total GAGs has been used as an established measure for the diagnosis of mucopolysaccharidoses (MPSs). Heparan sulfate (HS),...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: Mashima, Ryuichi, Sakai, Eri, Tanaka, Misa, Kosuga, Motomichi, Okuyama, Torayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908047/
https://ncbi.nlm.nih.gov/pubmed/27331006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2016.03.009
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